Variations in skin temperatures are translated into variations in light intensity .• This model can be piloted to replicate clinical scenarios Benefits: The integration of thermal risk in medical and nursing care   Read more

This technology relates to novel aminopyridinemethanol compounds, obtained by an enantioselective synthesis.This family compounds demonstrated a strong antimalarial activity at nanomolar concentrations. Benefits: A strong antimalarial activity on... Read more

Treatment of dry eye syndrome, uveitis,…in animals New formulation of cyclosporine eye drops with concentration up to 20mg/mLSimple formulation : 1 API + 1 excipient Benefits: Single dose No alcoolic solvent No preservative Economic and easy... Read more

Treatment of dry eye syndrome, uveitis…. New formulation of cyclosporine eye drops with concentration up to 20mg/mLSimple formulation : 1 API + 1 excipient Benefits: Single dose No alcoolic solvent No preservative Economic and easy to produce... Read more

The invention consists in coupling the measurement of intra-vaginal or intra-rectal pressure under stress with dynamic MRI to observe and quantify the movement movement induced by this solicitation.The measurement of the couple pressure/displacement... Read more

The miRNA research field is of interest for the future and is now well established that miRNAs represent new potential therapeutic targets as well as relevant diagnostic / prognostic biomarkers. Nearly 60% of patients with non-small cell lung cancer... Read more

Dive technology consist in a dopaminergic stimulation by continuous intra-cerebro ventricular delivery of anaerobic dopamine, in the third ventricle, closed to the target of the nigro-striatal system in Parkinson's disease at the stage of motor fluct... Read more

Platelets constitute abundant, natural, readily accessible sources of physiological mixtures of numerous growth factors (GFs) with proven effects on cell survival and proliferation. Platelet lysates (PL) are already used in several fields of human r... Read more

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An autofocus system for femto/pico second pulsed lasers based on the coherence between incident and reflected light from the sample. Benefits: Automatic focusing : no human intervention (delay line embedded) Accurate : the sample is in the exact... Read more

The developed device is composed of a cylindrical active sensor allowing a thermal solicitation of the studied material.This heat flux device is based on the thermo-electrical principles in order to control and measure the thermal flux provided to th... Read more

This system based on a capacitive sensor integrated in the front face of a vehicle allows to detect a pedestrian (by modification of the electric field generated by the sensor on a short range) and offer the capability to trigger a protection device... Read more

It is known for cancers that there is a tight relation between patient’s favorable evolution and the capacity to remove the totality of cancer cells. Despite the large panel of different technologies available in the operating room, it is still extre... Read more

Measurement method based on echocardiography Benefits:  Non invasive Reliability comparable to the thermodilution technique Non operator dependent Easy to Operate Automatable   Read more

New formulation of amiodarone adapted to pediatrics for the treatment of supraventricular tachycardia Benefits: Liquid formulation for oral administration Easy to adapt the dosage Opportunity to benefit from incentive measures for the developme... Read more

This MicroElectroMechanical System (MEMS) allows the remote manipulation of particles, cells and droplets lying in a liquid sample with a high selectivity (one particle can be selected and moved independently of its neighbors).This technology relies... Read more

The Invasive Fungal Infections (IFI) are associated with higher mortality in hospitals. These infectious diseases are severe. Early and appropriate treatment is crucial for improving prognosis. Currently, the diagnosis of IFI is difficult to estab... Read more

The laser is made of a single source and is designed to induce a 4-wave mixing effect by the spectral focusing technique, to make Raman analysis be biocompatible through the Stimulated Raman microscopy. It allows the vibration frequency of interest t... Read more

This new process allows the production of higher molecular weight pyroglutamic esters in quantitative yields from pyroglutamic acid or from “light” pyroglutamic esters Benefits: Our efficient process allows the production of pyroglutamic esters wit... Read more

Detection and classification of liver fibrosis from serum by Fourier Transform Infrared spectroscopy (FTIR)Detection method, gradation (F0-F4) and monitoring of liver fibrosis from serum. Allows the identification of patients with a risk of hepatocel... Read more

Flip top cap with screw neck diameter 27mm, non removable from vial, with connection system to EN FIT syringe, with air intake filter and one way valve. Benefits: Security of the oral way.   No risk of contamination by ambient air due to... Read more

Hydroxyapatite root canal model for Endodontic research and training use. This model presents equivalent architectures, porosity, hardness as a natural tooth, which allows dental simulation training in « real condition ». Benefits:  Method of pr... Read more

Current quantification technique is based on the subjective analysis by a pathologist of stained slides from biopsies. It requires a significant phase for sample preparation and is not reproducible due to the great variability intra and between opera... Read more

TAX2 is a new peptide-based drug with anti-angiogenic properties, designed through innovative interdisciplinary approaches (bioinformatics, molecular modeling, biochemical and molecular biology). The peptide has specific antagonistic properties of t... Read more

The laser is composed of an optoelectronic infrared quantum cascade laser (QCL) pump and a gas compartment. It emits a TeraHertz (THz) continuous wave (CW) beam tunable with discrete frequency values from 0.7 to 1.2 THz and works at room temperature.... Read more

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This new family of glasses doesn't need any variation of temperature for self-healing Benefits : no variation of temperature needed for self healing processCoefficient of Thermal Expansion (CTE) compatibility with other components in SOFCCompatibil... Read more

This new technology accurately determines the average temperature of a coil used in an electrical display (motor, generator…) without any sensor. This device just requires to be plugged on the terminal block of the electrical device Benefits : ... Read more

K1 Dimer (Kringle domain of HGF/SF) as a potent agonist of METThe development of MET receptor agonists is an important goal in regenerative medicine. Up to now, many studies aiming at developing MET agonists forregenerative medicine focused on the de... Read more

Portable ankle ergometer with no muscle compensation B.O.T.T.E : (Boot Design, Open Chain, Three Dimensions,Transportable Ergometer) Benefits :  Returns the real value of the force developed in the ankle, the patient cannot take support on other... Read more

Our laboratory has developed eWeWeW, a scientific software simulating thin-film transistors (TFT) electrical characteristics in a very fast and user-friendly way. eWeWeW is versatile thanks to its unique user interface allowing a gradual approach to... Read more

New Atomic Force Microscopy (AFM) based technic to accurately measure the surface electric potential profile of devices in their operating conditions (biased). It is a nondestructive process.Measurements can be performed in ambient conditions, thanks... Read more

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CodImpulse is a software solution able to reduce impulsive noise in telecommunication systems. This method implements soft iterative decoders based on log likelihood ratio calculation. Technically, it is based on an efficient channel coding embedded... Read more

AlgoPath is a 3D Serious Game that helps learn fundamentals of computing without even typing a single line of code.The player is immersed in a virtual environment dedicated to roads construction where every object he/she can see (such as huts, houses... Read more

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New process and catalyst for green dry methane reforming This new process associated with a specific catalyst solve coking problems.The syngas is produced in optimal conditions for further transformations. Benefits : CO2 as reactant No catalyst... Read more

This new material called BIOPOLEMBAL is fully agro-based and biodegradable thanks to its mix of PLA, PBS and PHA and some other agro based additives.It can be used for the soft tube packaging to replace Polyethylene (PE). Benefits: Our patented mat... Read more

high performance vinylester resin made up of acrylate monomers, high-Tg thermoplastic polymer and reactive solvent.The use of a high-Tg thermoplastic polymer (polyethersulfone) into the formulation enables to get vinylester resins with enhanced mecha... Read more

Main characteristics : Single-component adhesive from animal protein Ready to use on wood surfaces : oak wood, Douglas pin, plywood Moisture resistant: consistent with green wood surfaces Adhesive performances competitives with fossil based glu... Read more

Main characteristics : Single-component adhesive from animal protein Ready to use on wood surfaces and consitent with green wood’s one Adhesive performances competitives with fossil based glues This yellow polymere provides promising adhesive... Read more

Agro-based thermosetting polymer with plant or animal derived proteins.Designed in an eco-efficient fast process, at low pressure and temperature. Benefits : Agro-based polymer as a substitute for petroleum-derived binder or plastic materials. H... Read more

Irradiance is a factor to be considered in the application of different cosmetics on skin. It is important for cosmetic to anticipate any change or improvement of theskin. To date, there is no simple technique to quantify the irradiance of a face, to... Read more

This system must be coupled to a in-situ traction device, to observe the behavior of the sample drawn during any phase traction .The software analyses images and can achieve a control imaging devices (and/or traction machine) according to the course... Read more

This microdevice creates a flow through a microfluidic system without pumping chamber nor valves.The flow is created by the oscillations of a flexible polymer membrane (Silastic S).This membrane is specifically drilled to force fluid flowing.The osci... Read more

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Immunotherapeutic strategy for inflammatory and auto-immune diseases using P28GST, a unique parasite - derived enzymeP28GST is an anti –oxidant enzymatic protein identified in schistosomes which displays potent anti-inflammatory and pro-Th2 immunogen... Read more

Combinatorial therapy to circumvent resistance mechanisms in the case of breast cancers.The proposed technology can overcome the development of resistance to treatment in the case of breast cancer therapy failure (30% of cases) by blocking a newly id... Read more

Type 4 Phosphodiesterases (PDE-4) are a major subfamilies of PDE enzymes present in inflammatory and immune cells, bronchial smooth muscle and brain. Inhibition of PDE4 activity results in the bronch by anti-inflammatory effects in combination with a... Read more

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This excipient improves the solubility of poorly soluble active ingredients while improving their bioavailability (Simvastatine, Ibuprofen, Piroxicam...) This excipient shows excellent compressive properties making it an excipient of choice for ta... Read more

Original technique for rapid and reliable detection by pyrosequencing method of chromosomal quinolone resistance in Enterobacteriaceae families with a clinical interest in human and veterinary medicine.This tool for rapid detection of Quinolone Resis... Read more

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New drugs with neuroprotective and anti-inflammatory properties targeting selective intracellular receptor.The Sigma-1 receptors (σ1R) correspond to a single class of transmembrane receptors located into endoplasmic reticulum. Expressed in the centra... Read more

Design of a subunit vaccine administered by mucosal or intradermal route and using polysaccharidic nanoparticles with lipidic heart. The nanoparticles are able to deliver the antigens to the immune cells and induce a strong cellular response protect... Read more

This technology is developed for Permanent or Low Dose Rate (LDR) Brachytherapy and prostate biopsy. The autonomous robot performing treatment or diagnosis is composed of :A robot arm: Low Space requirement Manual control available An operati... Read more

New active ingredient stimulating skin cells regeneration for cosmetic use: anti aging facial-care.Neutral, high molecular weight, water soluble oligosaccharides from flax seed mucilage.Cosmetic Claims: Prevention and struggle against skin aging than... Read more

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