Description
The Prodynov photosensitizer is a third-generation PS.
It targets folate receptors that are overexpressed in cancer cells of the ovaries, liver, and pancreas...
The proof of concept (POC) study focused on peritoneal carcinomatosis.
When exposed to light, this photosensitizer has a threefold effect:
- Making cancer cells visible through fluorescence and enabling their surgical removal
- Lysis of tumor cells that are not accessible by surgery
- Immune System Activation
- Soluble in water; more effective than 5-ALA
- "Pre-GMP" Synthesis in 3 Steps with Detailed Procedures for the Optimized Synthesis
- Analytical method for the identification, quantification, and determination of product purity
- Method for Solubilization and Preformulation
- In vitro and in vivo ADME-TOX, DMT, PK, Efficacy in mice and pigs
IP: 1 Patent TRL: In vivo POC (4/5) Partnership: Licensing Agreement