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WAVEIMMUNE: New PD-L1 immune checkpoint inhibitors for the treatment of a wide range of cancers.

Description

Main compound administered orally

Anti-PD-1/PD-L1 immunotherapy has become a key strategy in the fight against cancer, aimed at reprogramming or activating the body’s anti-tumor immune response to destroy tumor cells without harming healthy cells.

 WAVEIMMUNE compounds are small-molecule PD-L1 inhibitors that have shown promising results in vitro and in vivo:

•AliPD1 is the lead compound in the series
•In vitro binding to the target
•Significant reduction in tumor volume in vivo in colorectal carcinoma

Partnership: Startups Seeking Funding

IP: PCT, Priority Date: June 30, 2024

Currently:

In vivo proof of concept in other models

Studies on the mechanism of action

Fact sheet

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Domains

Medical and health technologies